Psilocybin clinical trials in Texas
8 trials with 12 study sites in Texas, recruiting or not yet recruiting, read from ClinicalTrials.gov on 28 October 2026. The site in Texas is named under each trial.
- RecruitingPhase 2NCT06132178
Psilocybin rTMS for Treatment Resistant Depression
Treatment Resistant Depression, MDD, Major Depressive Disorder · University of Texas at Austin · Ages 22 to 65
Austin, Texas, United States
In Texas: Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600, Austin
- RecruitingPhase 2NCT06200155
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
Depression, Anxiety, Psilocybin-Assisted Psychotherapy, Advanced Cancer · M.D. Anderson Cancer Center · Ages 25+
Houston, Texas, United States
In Texas: MD Anderson Cancer Center, Houston
- RecruitingPhase 2NCT06706232
Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality
Bipolar II Disorder, Depression, Bipolar, Suicidality · The University of Texas Health Science Center, Houston · Ages 25 to 70
Houston, Texas, United States
In Texas: The University of Texas Health Science Center at Houston, Houston
- RecruitingPhase 3NCT06793397
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder · Cybin IRL Limited · Ages 18 to 85
79 sites in 8 countries
In Texas: Austin Clinical Trial Partners, Austin; Adams Clinical Dallas, DeSoto; North Texas Clinical Trials, Fort Worth; Brain Health Consultants and TMS Center, Houston; Flourish Research San Antonio, San Antonio
- RecruitingPhase 2NCT06801041
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
Depression, Anxiety, Cancer · M.D. Anderson Cancer Center · Ages 18+
Houston, Texas, United States
In Texas: The University of Texas M. D. Anderson Cancer Center, Houston
- RecruitingPhase 2NCT06888128
State-Funded Trial Assessing Recovery and Long-Term Impact of Guided Psilocybin for Healing Trauma
PTSD · Baylor College of Medicine · Ages 21 to 64
Houston, Texas, United States
In Texas: Baylor College of Medicine, Houston
- Not yet recruitingPhase 1 / Phase 2NCT07079852
The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function
Healthy · Manoj Doss · Ages 21 to 45
Austin, Texas, United States
In Texas: The University of Texas at Austin Dell Medical School, Austin
- Not yet recruitingPhase 2NCT07227909
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
Psilocybin, Neuropathy · M.D. Anderson Cancer Center · Ages 18+
Houston, Texas, United States
In Texas: MD Anderson Cancer Center, Houston
How joining a trial works
- Free to take part
- Trials generally cost participants nothing for the study drug and the study visits, and some pay for travel or time. Check what a study covers on its registry page.
- Screened first
- Every study screens volunteers with questionnaires, medical history and often a physical and psychiatric check. Many people who apply are not enrolled.
- Eligibility is strict
- Common exclusions include a personal or family history of psychosis or bipolar disorder, some heart conditions, pregnancy and certain medications, which you may be asked to stop under medical supervision. Never stop a medication on your own to qualify.
- You may get a placebo
- Many trials compare psilocybin with a placebo or a low dose, and you may not be told which you had until the study ends.
- Contact the study team through the registry
- Each registry record lists the study contacts and sites. We do not republish personal emails or phone numbers; use the link on each trial page.
- Not medical advice
- This is a list of registry records, not a recommendation. Talk to your doctor before applying. Disclaimer · Safety and medications
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine, read 28 October 2026. Filter: overall status RECRUITING or NOT_YET_RECRUITING; an intervention named psilocybin, psilocin, COMP360 or CYB003. Refreshed weekly; a study's own registry page is always the current record.