Psilocybin clinical trials in Connecticut
8 trials with 9 study sites in Connecticut, recruiting or not yet recruiting, read from ClinicalTrials.gov on 28 October 2026. The site in Connecticut is named under each trial.
- RecruitingPhase 1NCT06160284
Exploration of Synaptotrophic Effects of Psilocybin in Opioid Use Disorder (OUD)
Opioid Use Disorder · Yale University · Ages 25 to 55
New Haven, Connecticut, United States
In Connecticut: Yale University, New Haven
- RecruitingPhase 1NCT06442423
Open-Label Psilocybin Study in Transdiagnostic Population
Transdiagnostic, Depression - Major Depressive Disorder, Anxiety · Yale University · Ages 18+
New Haven, Connecticut, United States
In Connecticut: Connecticut Mental Health Center - Yale School of Medicine, New Haven
- RecruitingEarly phase 1NCT06464367
Mechanistic Studies of Psilocybin in Headache Disorders
Migraine · Yale University · Ages 21 to 70
West Haven, Connecticut, United States
In Connecticut: VA Connecticut Healthcare System, West Haven
- RecruitingPhase 3NCT06793397
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder · Cybin IRL Limited · Ages 18 to 85
79 sites in 8 countries
In Connecticut: Yale School of Medicine - Yale Program for Psychedelic Science, New Haven
- RecruitingEarly phase 1NCT07118332
Psilocybin as a Treatment for Chronic Pain in Smokers
Smokers With Chronic Pain · Yale University · Ages 21 to 65
2 sites in United States (West Haven)
In Connecticut: Department of Veterans Affairs, West Haven; Department of Veterans Affairs, West Haven
- RecruitingPhase 2NCT07610369
The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease
Depression, Parkinson's Disease (PD) · Yale University · Ages 40 to 80
New Haven, Connecticut, United States
In Connecticut: Yale University, New Haven
- Not yet recruitingPhase 2NCT07306364
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin · Yale University · Ages 21 to 65
New Haven, Connecticut, United States
In Connecticut: Connecticut Mental Health Center, New Haven
- Not yet recruitingPhase 1NCT07693153
The Effects of Psilocybin on Social Connectedness
Loneliness, Grief · Yale University · Ages 21 to 65
New Haven, Connecticut, United States
In Connecticut: Connecticut Mental Health Center, New Haven
How joining a trial works
- Free to take part
- Trials generally cost participants nothing for the study drug and the study visits, and some pay for travel or time. Check what a study covers on its registry page.
- Screened first
- Every study screens volunteers with questionnaires, medical history and often a physical and psychiatric check. Many people who apply are not enrolled.
- Eligibility is strict
- Common exclusions include a personal or family history of psychosis or bipolar disorder, some heart conditions, pregnancy and certain medications, which you may be asked to stop under medical supervision. Never stop a medication on your own to qualify.
- You may get a placebo
- Many trials compare psilocybin with a placebo or a low dose, and you may not be told which you had until the study ends.
- Contact the study team through the registry
- Each registry record lists the study contacts and sites. We do not republish personal emails or phone numbers; use the link on each trial page.
- Not medical advice
- This is a list of registry records, not a recommendation. Talk to your doctor before applying. Disclaimer · Safety and medications
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine, read 28 October 2026. Filter: overall status RECRUITING or NOT_YET_RECRUITING; an intervention named psilocybin, psilocin, COMP360 or CYB003. Refreshed weekly; a study's own registry page is always the current record.