Psilocybin clinical trials in Massachusetts
4 trials with 4 study sites in Massachusetts, recruiting or not yet recruiting, read from ClinicalTrials.gov on 28 October 2026. The site in Massachusetts is named under each trial.
- RecruitingPhase 3NCT06247839
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder
Major Depressive Disorder · Sharmin Ghaznavi · Ages 18 to 55
Charlestown, Massachusetts, United States
In Massachusetts: Athinoula A. Martinos Center for Biomedical Imaging, Charlestown
- RecruitingPhase 3NCT06793397
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder · Cybin IRL Limited · Ages 18 to 85
79 sites in 8 countries
In Massachusetts: Adams Clinical Boston, Boston
- RecruitingPhase 1NCT07516405
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
Healthy Volunteer, Older Adults (65-85 Years) · University of Colorado, Denver · Ages 65 to 85
6 sites in United States
In Massachusetts: Dana-Farber Cancer Institute, Boston
- Not yet recruitingPhase 2NCT07296094
Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder
Alcohol Use Disorder · Brigham and Women's Hospital · Ages 18 to 65
Boston, Massachusetts, United States
In Massachusetts: Brigham and Women's Hospital, Boston
How joining a trial works
- Free to take part
- Trials generally cost participants nothing for the study drug and the study visits, and some pay for travel or time. Check what a study covers on its registry page.
- Screened first
- Every study screens volunteers with questionnaires, medical history and often a physical and psychiatric check. Many people who apply are not enrolled.
- Eligibility is strict
- Common exclusions include a personal or family history of psychosis or bipolar disorder, some heart conditions, pregnancy and certain medications, which you may be asked to stop under medical supervision. Never stop a medication on your own to qualify.
- You may get a placebo
- Many trials compare psilocybin with a placebo or a low dose, and you may not be told which you had until the study ends.
- Contact the study team through the registry
- Each registry record lists the study contacts and sites. We do not republish personal emails or phone numbers; use the link on each trial page.
- Not medical advice
- This is a list of registry records, not a recommendation. Talk to your doctor before applying. Disclaimer · Safety and medications
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine, read 28 October 2026. Filter: overall status RECRUITING or NOT_YET_RECRUITING; an intervention named psilocybin, psilocin, COMP360 or CYB003. Refreshed weekly; a study's own registry page is always the current record.