Psilocybin clinical trials in New York
14 trials with 20 study sites in New York, recruiting or not yet recruiting, read from ClinicalTrials.gov on 28 October 2026. The site in New York is named under each trial.
- RecruitingPhase 2 / Phase 3NCT05398484
Psilocybin Therapy in Advanced Cancer
Advanced Cancer · NYU Langone Health · Ages 21 to 100
2 sites in United States (Aurora, New York)
In New York: NYU Langone Health, New York
- RecruitingPhase 2NCT05452772
5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
Tobacco Use Disorder · Johns Hopkins University · Ages 21+
3 sites in United States (Birmingham, Baltimore, New York)
In New York: New York University, New York
- RecruitingPhase 2NCT06349083
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
Alcohol Use Disorder · NYU Langone Health · Ages 18 to 65
New York, New York, United States
In New York: NYU Langone Health, New York
- RecruitingPhase 2NCT06592833
Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder
Major Depressive Disorder · Icahn School of Medicine at Mount Sinai · Ages 21 to 80
New York, New York, United States
In New York: Icahn School of Medicine at Mount Sinai, Center for Psychedelic Therapy Research, New York
- RecruitingPhase 3NCT06793397
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder · Cybin IRL Limited · Ages 18 to 85
79 sites in 8 countries
In New York: Adams Clinical Harlem, New York; New York State Psychiatric Institute, New York; Davis Clinical (Adams Clinical Bronx), The Bronx; Adams Clinical Watertown, Watertown
- RecruitingPhase 2NCT06796062
Psilocybin for Opioid Use Disorder (OUD)
Opioid Use Disorder · NYU Langone Health · Ages 18 to 65
5 sites in United States
In New York: StartCare, Brooklyn; NYU Langone Health, New York; VIP Community Services, Inc, The Bronx
- RecruitingPhase 2NCT06899165
Psilocybin-Assisted Therapy for Intergenerational Trauma
Psychological Stress, Depression, Anxiety · Rachel Yehuda · Ages 18+
New York, New York, United States
In New York: The Parsons Research Center for Psychedelic Healing, New York
- RecruitingPhase 1 / Phase 2NCT07251491
Psilocybin to Treat Depression in Spinal Cord Injury
Spinal Cord Injury, Depression - Major Depressive Disorder, Veteran · James J. Peters Veterans Affairs Medical Center · Ages 22+
The Bronx, New York, United States
In New York: James J. Peters Department of Veterans Affairs Medical Center, The Bronx
- RecruitingPhase 1NCT07516405
Safety and Tolerability Trial of Psilocybin in Healthy Older Adults
Healthy Volunteer, Older Adults (65-85 Years) · University of Colorado, Denver · Ages 65 to 85
6 sites in United States
In New York: New York University Langone Health, Center for Psychedelic Medicine, New York
- RecruitingPhase 2 / Phase 3NCT07570654
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms · COMPASS Pathways · Ages 18+
10 sites in 2 countries
In New York: NY, New York; NY, The Bronx
- RecruitingPhase 1NCT07607938
Psilocybin as a Novel Therapy for Residual Anhedonia
Anhedonia, Emotional Blunting · NYU Langone Health · Ages 18 to 65
New York, New York, United States
In New York: NYU Langone Health, New York
- Not yet recruitingEarly phase 1NCT06760533
Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)
IBS - Irritable Bowel Syndrome · NYU Langone Health · Ages 18 to 75
New York, New York, United States
In New York: NYU Langone Health, New York
- Not yet recruitingPhase 2NCT06827054
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm · Roswell Park Cancer Institute · Ages 18 to 75
Buffalo, New York, United States
In New York: Roswell Park Cancer Institute, Buffalo
- Not yet recruitingPhase 2NCT07296328
Effects of Psilocybin on Speech Fluency, Struggle, and Brain Activity in People Who Stutter
Stuttering · NYU Langone Health · Ages 18 to 50
New York, New York, United States
In New York: NYU Langone Health, New York
How joining a trial works
- Free to take part
- Trials generally cost participants nothing for the study drug and the study visits, and some pay for travel or time. Check what a study covers on its registry page.
- Screened first
- Every study screens volunteers with questionnaires, medical history and often a physical and psychiatric check. Many people who apply are not enrolled.
- Eligibility is strict
- Common exclusions include a personal or family history of psychosis or bipolar disorder, some heart conditions, pregnancy and certain medications, which you may be asked to stop under medical supervision. Never stop a medication on your own to qualify.
- You may get a placebo
- Many trials compare psilocybin with a placebo or a low dose, and you may not be told which you had until the study ends.
- Contact the study team through the registry
- Each registry record lists the study contacts and sites. We do not republish personal emails or phone numbers; use the link on each trial page.
- Not medical advice
- This is a list of registry records, not a recommendation. Talk to your doctor before applying. Disclaimer · Safety and medications
Source: ClinicalTrials.gov API v2, U.S. National Library of Medicine, read 28 October 2026. Filter: overall status RECRUITING or NOT_YET_RECRUITING; an intervention named psilocybin, psilocin, COMP360 or CYB003. Refreshed weekly; a study's own registry page is always the current record.