Psilocybin law in Oregon

State-licensed programme Checked 26 October 2026

Psilocybin is legal in Oregon only through the state-licensed psilocybin services program for adults 21 and older (ORS 475A); outside that program it remains a Schedule I controlled substance and possession of under 12 grams is a drug enforcement misdemeanor under ORS 475.752.

The state licenses supervised adult use at licensed centres. Psilocybin stays a Schedule I drug under US federal law. A summary of published sources, not legal advice.

Source status: Licensed adult use. Psilocybin remains a Schedule I drug under US federal law.

Scheduling

Psilocybin and psilocyn are Schedule I controlled substances in Oregon: OAR 855-080-0021 adopts the federal Schedule I list in 21 CFR 1308.11, which includes psilocybin (1308.11(d)(29)) and psilocyn (1308.11(d)(30)); ORS 475.005(6) and 475.035 tie Oregon's schedules to the federal ones as modified by the Board of Pharmacy. [Or. Admin. Code 855-080-0021, Schedule I, Legal Information Institute, Cornell Law School, read 26 October 2026] [21 CFR 1308.11, Schedule I, Legal Information Institute, Cornell Law School, read 26 October 2026] [ORS Chapter 475, Controlled Substances (2025 Edition), Oregon State Legislature, 2025, read 26 October 2026]

What the law says

Ballot Measure 109, approved by voters in November 2020 and codified as ORS 475A, created a regulated program for manufacturing psilocybin products and providing psilocybin services; ORS 475A.210 to 475A.722 are cited as the Oregon Psilocybin Services Act. [Oregon Psilocybin Services, Oregon Health Authority, read 26 October 2026] [ORS Chapter 475A, Psilocybin Regulation (2025 Edition), Oregon State Legislature, 2025, read 26 October 2026]
The program is run by Oregon Psilocybin Services in the Oregon Health Authority; on 1 September 2026 it merged with the Oregon Medical Marijuana Program to form the Medical Cannabis and Psilocybin (MCAP) Section. [Oregon Psilocybin Services, Oregon Health Authority, read 26 October 2026]
Services are for adults: ORS 475A.440 says a licensee may not sell or deliver a psilocybin product to a person under 21 years of age. [ORS Chapter 475A, Psilocybin Regulation (2025 Edition), Oregon State Legislature, 2025, read 26 October 2026]
The first licensed psilocybin service centers opened in summer 2023; by December 2024, 31 licensed service centers were operating and about 8,000 clients were expected to have had a session by the end of 2024. [Oregon psilocybin industry will focus on fine-tuning first-in-the-nation program in 2025, OPB, 2024-12-14, read 26 October 2026]
Cities and counties may prohibit psilocybin businesses by referring an ordinance to voters (ORS 475A.718). [ORS Chapter 475A, Psilocybin Regulation (2025 Edition), Oregon State Legislature, 2025, read 26 October 2026]
Measure 110 (2020) made possession of small amounts of controlled substances a Class E violation; HB 4002 (2024) repealed that violation and replaced it with a new misdemeanor of unlawful possession, effective 1 September 2024. [HB 4002 and HB 5204, Relating to Opioid Addiction in Oregon (fact sheet), Oregon Health Authority, 2024, read 26 October 2026]
HB 2387 (2025) lets licensees of seven health professional boards also act as licensed psilocybin facilitators, and limits disclosure of information from Oregon Health Authority investigations; it became 2025 Or. Laws ch. 147. [HB 2387 (2025 Regular Session), measure overview, Oregon State Legislature, read 26 October 2026] [Enrolled House Bill 2387 (2025), Oregon State Legislature, 2025, read 26 October 2026]

Penalties

Possessing a Schedule I substance, including under 12 grams of psilocybin or psilocin, is a drug enforcement misdemeanor (ORS 475.752(3)(a)); under ORS 475.896 the court may not impose a fine and sentences supervised probation of up to 18 months, with up to 180 days of jail only at the defendant's request or on probation revocation. [ORS Chapter 475, Controlled Substances (2025 Edition), Oregon State Legislature, 2025, read 26 October 2026]
Possessing 12 grams or more of a mixture containing psilocybin or psilocin is a Class A misdemeanor (ORS 475.752(7)(a)(B)). [ORS Chapter 475, Controlled Substances (2025 Edition), Oregon State Legislature, 2025, read 26 October 2026]
A person charged with a drug enforcement misdemeanor may enter conditional discharge probation of 12 months, after which the charge is dismissed with prejudice (ORS 475.897). [ORS Chapter 475, Controlled Substances (2025 Edition), Oregon State Legislature, 2025, read 26 October 2026]

Bills

HB 2387 2025
Relating to psilocybin; and declaring an emergency
Allows licensees of certain health professional regulatory boards to provide psilocybin services as licensed facilitators and makes OHA psilocybin investigation records confidential.
Status: Signed 22 May 2025; 2025 Or. Laws ch. 147, effective on signing (emergency clause), 22 May 2025

Licensed centres in Oregon

Dated changes

22 May 2025: Allows licensees of certain health professional regulatory boards to provide psilocybin services as licensed facilitators and makes OHA psilocybin investigation records confidential. Status: Signed 22 May 2025; 2025 Or. Laws ch. 147, effective on signing (emergency clause). Source
November 2024: Local bans on psilocybin businesses passed in 16 of the 17 Oregon places that voted on them in the November 2024 election. Source
2 January 2023: The Oregon Health Authority opened licence applications for psilocybin service centers, facilitators, manufacturers and laboratories under OAR chapter 333, division 333. Licensed service centers began opening to clients in summer 2023. Source
November 2022: Under ORS 475A.718 local opt-outs, 25 counties and 26 cities banned psilocybin businesses at the November 2022 election, as OPB reported. Source
November 2020: Voters approved Ballot Measure 109, codified as ORS 475A, directing the Oregon Health Authority to license and regulate psilocybin products and psilocybin services. Source

The full law map, with 51 US entries and every country we cover, or every dated change.