Psilocybin law in Iowa
Illegal Checked 26 October 2026
Psilocybin is illegal in Iowa: it is a Schedule I controlled substance under Iowa Code 124.204, and a first offense of possession is a serious misdemeanor.
Psilocybin is a controlled substance with no lawful route for retreats or personal use. Some of these states fund research or trials. A summary of published sources, not legal advice.
Source status: Prohibited. Psilocybin remains a Schedule I drug under US federal law.
Scheduling
Psilocybin and psilocyn are listed as hallucinogenic substances in Schedule I, Iowa Code 124.204(4)(s) and (t). [Iowa Code 124.204, Schedule I - substances included, Iowa Legislature, read 26 October 2026]
What the law says
- Governor Kim Reynolds vetoed HF 383, a crystalline polymorph psilocybin bill that passed the House 92-0 and the Senate 47-0, on 11 June 2025. [Bill History for House File 383 (91st GA), Iowa Legislature, 2025-06-11, read 26 October 2026]
- HF 978, which would have created a regulated system for producing and administering psilocybin, passed the House 84-6 on 21 April 2025 but never received a Senate floor vote. [Bill History for House File 978 (91st GA), Iowa Legislature, 2026-05-01, read 26 October 2026]
Penalties
- Knowingly or intentionally possessing a controlled substance without a valid prescription is a serious misdemeanor for a first offense, an aggravated misdemeanor with one prior drug conviction, and a class D felony with two or more priors (Iowa Code 124.401(5)(a)). [Iowa Code 124.401, Prohibited acts - manufacturers - possessors - counterfeit substances, Iowa Legislature, read 26 October 2026]
Bills
HF 978 2025-2026 (91st General Assembly)
A bill for an act relating to the production and administration of psilocybin, and providing penalties
Would have created a regulated system to produce psilocybin and administer it to patients.
Status: Passed House 21 April 2025; reported by Senate Ways and Means with amendment 1 May 2026; no Senate vote before adjournment, 1 May 2026
HF 2085 2025-2026 (91st General Assembly)
A bill for an act relating to the production and administration of psilocybin and providing penalties
Would have created a regulated psilocybin production and administration system.
Status: Referred to House Health and Human Services; subcommittee meeting set for 26 January 2026 was cancelled; died, 22 January 2026
SF 2151 2025-2026 (91st General Assembly)
A bill for an act removing psilocybin and psilocyn from the list of schedule I controlled substances
Would have removed psilocybin and psilocyn from Schedule I.
Status: Assigned to Senate Health and Human Services subcommittee 5 February 2026; died, 5 February 2026
HF 383 2025-2026 (91st General Assembly)
A bill for an act relating to the controlled substance crystalline polymorph psilocybin
Addressed the status of crystalline polymorph psilocybin under Iowa's controlled substances law.
Status: Passed House 92-0 and Senate 47-0; vetoed by Governor 11 June 2025, 11 June 2025
HF 351 2025-2026 (91st General Assembly)
A bill for an act removing psilocybin and psilocyn from the list of schedule I controlled substances
Would have removed psilocybin and psilocyn from Schedule I.
Status: Referred to House Public Safety 12 February 2025; died, 12 February 2025
Dated changes
- 1 May 2026: Would have created a regulated system to produce psilocybin and administer it to patients. Status: Passed House 21 April 2025; reported by Senate Ways and Means with amendment 1 May 2026; no Senate vote before adjournment. Source
- 5 February 2026: Would have removed psilocybin and psilocyn from Schedule I. Status: Assigned to Senate Health and Human Services subcommittee 5 February 2026; died. Source
- 22 January 2026: Would have created a regulated psilocybin production and administration system. Status: Referred to House Health and Human Services; subcommittee meeting set for 26 January 2026 was cancelled; died. Source
- 11 June 2025: Addressed the status of crystalline polymorph psilocybin under Iowa's controlled substances law. Status: Passed House 92-0 and Senate 47-0; vetoed by Governor 11 June 2025. Source
- 12 February 2025: Would have removed psilocybin and psilocyn from Schedule I. Status: Referred to House Public Safety 12 February 2025; died. Source
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